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Cell Culture > Cytokines and Growth factors
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Cytokines and Growth factors
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Angiogenesis, Apoptose, Cancerogenesis, Development, Differentiation, Hematopoïesis, Inflammation, ... many tools for studies on cytokine effect, detection or quantification!
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Proteins
For your research on cytokines and growth factors, we offer specific tools for various study models and applications.
Our line includes the following protein families:
- Adipokines
- Chemokines
- Defensins
- FGFs
- Immunoregulatory Proteins
- Interferons
- Interleukins, CSFs, Growth Factors
- Neurotrophins
- TGFß / BMP Proteins
- TNF Ligands / Receptors
- Other recombinant proteins
These proteins are specific for various cell lines and species (human, mouse or rat). They are supplied in lyophilized form, making the products more stable and easy to handle and store.
Some applications
Cell type :Human Dendritic Cells (DC)
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| BRU-GM-CSF-RES |
GMCSF, research grade
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Ag |
50 µg |
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| BRU-IL-4-RES |
IL4, research grade
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Ag |
50 µg |
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Cell type :Human Embryonic Stem Cells (hESC)
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| P100-18B |
FGF basic (FGF-2; bFGF)
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Ag |
50 µg |
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NEW PRODUCTS 
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Caracteristics : 9.0 kDa monomeric protein, containing 80 amino residues
Biological activities : Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| P100-50 |
Betacellulin (BTC)
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Ag |
20 µg |
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Caracteristics : 6.0 kDa monomeric protein, containing 50 amino residues
Biological activities : Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines.
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| P100-04 |
Epiregulin (EREG)
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Ag |
25 µg |
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Caracteristics : 36.2 kDa protein containing 331 amino acid residues
Biological activities : Elevated expression of NOV is associated with certain tumors, including Wilm's tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorgenicity and proliferation is correlated with decreased NOV expression. Additionally, NOV induces cell adhesion and cell migration by signaling through specific cell surface integrins and by binding to heparin sulfate proteoglycans and to fibulin 1C. NOV has also been reported to exert proangiogenic activities.
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| P120-26 |
NOV
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Ag |
20 µg |
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Caracteristics : 12.7 kDa globular protein containing 112 amino acid residues
Biological activities : OTOR appears to be involved in early chondrogenesis of the otic capsule, which is required for normal inner ear development and auditory function.
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| P130-03 |
OTOR (Otoraplin, MIAL)
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Ag |
20 µg |
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Caracteristics : 52.5 kDa protein containing 465 amino acid residues (isoform 1)
Biological activities : Visfatin exerts hypoglycemic effects by interacting with the insulin receptor. The circulating levels of Visfatin are much lower than those of insulin and are not affected by feeding, implying that the hypoglycemic effect of Visfatin may not be of physiological importance. The plasma Visfatin levels, like those of Leptin, correlate positively with the percent of body fat and increase during the development of obesity. Although the metabolic function of Visfatin is still unknown, it appears that this newly identified adipocytokine might play an important role, similar to that of Leptin, in the regulation of body weight, i.e. as an afferent signal reflecting excess body fat.
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| P130-09 |
Visfatin (PBEF: Pre-B cell colony-enhancing factor)
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Ag |
25 µg |
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Caracteristics : 38.4 kDa, non-glycosylated protein containing 343 amino acid residues
Biological activities : Elevated levels of Wnt proteins are associated with tumorigenesis and are present in numerous human breast cancers.
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Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| P120-17 |
Wnt-1
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Ag |
10 µg |
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Caracteristics : The apparent molecular weight is 28.9 kDa by mass spectrometry. It is a glycosylated 227 amino acid protein.
Biological activities : Granzyme B is required for the induction of target cell lysis, which occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| P140-03 |
Granzyme B
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Ag |
10 µg |
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Monoclonal and Polyclonal Antibodies, Biotinylated or not, are also available.
They are intented for use in ELISA, Neutralization, Western blot, ... experiments.
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