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Immunology > Veterinary
The Acute Phase Response In Animals.
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In the last several years there has been considerable progress in studies on the acute phase response as it affects animals. It is now established that the response is a result of pro-inflammatory cytokines being secreted into the circulation from sites of infection or inflammatory lesion. Among the many pathophysiological responses of an animal to stimulation is the increased production and secretion from the liver of the acute phase proteins involving activation of transcription factors in the hepatocyte and resulting in increased protein synthesis.The benefit to clinical diagnosis of analysis of the circulating concentration of the acute phase proteins has been established. In canine medicine the range of acute phase proteins being determined includes C-reactive protein (CRP), haptoglobin (Hp), and a1 acid glycoprotein (AGP) which are valuable biomarkers of inflammation and infection. In feline diagnosis the differentiation diagnosis of feline infectious peritonitis has benefited from determination of AGP concentrations. In bovine medicine, the principle acute phase protein to be used is Hp which is elevated in several important bovine infectious diseases. Using Hp in conjunction with serum amyloid A (SAA) and AGP determination of these biomarkers in serum allowed the differentiation of acute and chronic conditions. In the pig, elevated levels of proteins such as CRP, Hp and a pig specific Major Acute Phase protein (MAP) have been identified in experimental infection and inflammation.Future investigation of the acute phase proteins in animals will provide further information on the comparative differences between the molecular control of stimulated protein production; novel application in maintaining individual and herd health; the potential for monitoring minor changes in their concentration; assessment of negative acute phase responses; relation to genetic resistance to disease; use in experimental studies of infection and vaccine development.
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| TP-802 |
Serum Amyloid A assay
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kit |
96 wells |
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| TP-802M |
Murine Serum Amyloid A assay
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kit |
96 wells |
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| TP-801 |
Phase Haptoglobin Assay (colorimetric)
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kit |
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| TP-803 |
Canine C-Reactive (CRP) Protein EIA "ACCUPHASE"
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kit |
1x96 wells |
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| TA-901 |
Porcin C reactive Protein Assay
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kit |
1 x 96 wells |
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| TP-806-E |
Haptoglobin ELISA
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kit |
100 assays |
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| TP-805-R |
Rat a-1 Acid Glycoprotein (AGP) Assay
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kit |
100 assays |
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| TP-805-F |
Feline a-1 Acid Glycoprotein (AGP) Assay
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kit |
100 assays |
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| TP-805-C |
Canine a-1 Acid Glycoprotein (AGP) Assay
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kit |
100 assays |
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| TP-805-M |
Mouse a-1 Acid Glycoprotein (AGP) Assay
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kit |
100 assays |
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| TP-805-P |
alpha-1 acid glycoprotein (AGP) Assay
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kit |
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| TP-805-B |
Bovine a-1 Acid Glycoprotein (AGP) Assay
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kit |
100 assays |
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| TP-805-T |
Turkey a-1 Acid Glycoprotein (AGP) Assay
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kit |
100 assays |
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EquiTest - ES
One-Step Rapid Pregnancy/Foal Viability Test For Mares
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Equitest ES is an easy, rapid and convenient test for determining the pregnancy status of mares from 120 days after mating until the expected time of foaling. It is a self-contained test system designed to detect elevated pregnancy specific steroid concentrations, and thereby aid the determination of pregnancy status.
Equitest ES utilises an immunochromatographic procedure to measure serum/plasma concentrations of pregnancy specific steroids secreted by the foetal-placental unit in all breeds of horses. The test requires a volume of 0.1 to 0.2 ml of serum or plasma taken 120 days after mating through to expected foaling. The serum/plasma sample is dropped into the well of a plastic cassette which holds the test membrane. This starts a colour change chemical reaction which is completed within 5 to 10 minutes. Serum/plasma from a non-pregnant mare produces a visible red line and red dot on the test membrane, while only a single line is generated by serum/plasma from a pregnant mare.
Equitest ES can be used to pregnancy test all breeds of horses. It can also be used on donkeys. The test is particularly useful for pregnancy testing miniature mares where pregnancy diagnosis by rectal palpation or internal ultrasound scanning is not recommended because of their small size.
For more details, please contact us at :
(33) 01 40 03 89 14
infos@abcysonline.com
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