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Immunology > Cell Biology
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For your Cell Biology Research
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Our catalogue includes more than 3000 references, with a large choice of Antibodies, Antigens and kits in many fields of Cell Biology Research.
Here, a selection of our principal products :
(Ag: Antigen, Mc: Monoclonal, Pc : polyclonal)
INTEGRIN
Protein of the integrin family of cell surface heterodimeric receptors that mediates dynamic cell-to-cell as well as cell-to-matrix adhesion. Integrins function as mechanochemical sensors and transducers able to change rapidly and reversibly their adhesive functions by modulating their ligand-binding affinity. Each subunit has a large N-terminal extracellular domain followed by a transmembrane domain and a short C-terminal cytoplasmic region. Some subclasses of integrins share a common beta chain while having different alpha chains.
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| VMA1952 |
Integrin alpha3 [CD49c], clone P1B5 (Hu)
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P1B5 |
Mc |
100 µl |
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| AbC117-1864 |
Integrin beta 3
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Pc |
100 µl |
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| AbC117-5165 |
CD61
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F11 |
Mc |
0.25mg |
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| AbC103 |
LFA-1b (CD18)
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R3.3 |
Mc |
100 µg |
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| AbC104 |
Mac-1a (CD11b)
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LM2/1 |
Mc |
100 µg |
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| AbC112 |
p150,95 (CD11c)
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CBR-p150/4G1 |
Mc |
100 µg |
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CADHERIN
Cadherins are a family of animal glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherins preferentially interact with themselves in a homophilic manner in connecting cells; thus acting as both receptor and ligand. A wide number of tissue-specific forms of cadherins are known, for example:
- Epithelial (E-cadherin) (CDH1).
- Neural (N-cadherin) (CDH2).
- Placental (P-cadherin) (CDH3).
- Retinal (R-cadherin) (CDH4).
- Vascular endothelial (VE-cadherin) (CDH5).
- Kidney (K-cadherin) (CDH6).
- Cadherin-8 (CDH8).
- Cadherin-9 (CDH9).
- Osteoblast (OB-cadherin) (CDH11).
- Brain (BR-cadherin) (CDH12).
- T-cadherin (truncated cadherin) (CDH13).
- Muscle (M-cadherin) (CDH15).
- Kidney (Ksp-cadherin) (CDH16).
- Liver-intestine (LI-cadherin) (CDH17).
Target Species : Human
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| MLCA |
E-Cadherin (6F9)
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6F9 |
Mc |
1 ml |
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| MCADH |
E-Cadherin (5H9)
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5H9 |
Mc |
1 ml |
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| VMA1989 |
VE-Cadherin [CD144; Cadherin-5; 7B4 antigen], extracelluar domain, trypsin sensitive, clone BV6 (Hu, Ms, Bov)
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BV6 |
Mc |
100 µg |
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| AbC253 |
sVE-Cadherin ELISA Kit
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Kit |
1 x 96 wells |
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CAM
Cell Adhesion Molecules (CAMs) are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.
These proteins are tipically transmembrane receptors and are composed of three domains: an intracellular domain, that interacts with the cytoskeleton, a transmembrane domain and an extracellular domain, that interacts either with other CAMs of the same kind (homophilic binding) or with other CAMs or the extracellular matrix (heterophilic binding).
Immunoglobulin SuperFamily CAMs (IgSF CAMs) are either homophilic or heterophilic and bind integrins or different IgSF CAMs.
Here is a list of some molecules of this family:
- NCAMs Neural Cell Adhesion Molecules
- Intercellular adhesion molecules (ICAMs)
- VCAM-1 Vascular Cell Adhesion Molecule
- PECAM-1 Platelet-endothelial Cell Adhesion Molecule
- L1
- CHL1
Target species:Human
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| AbC0019 |
PSA-NCAM (PolySialic Acid-NCAM)
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2-2B |
Mc |
50 µl |
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| 0023-42005 |
VCAM-1
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1.G1b1 |
Mc |
100µg |
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| AbC117-249 |
CD54 (ICAM-1)
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1H4 |
Mc |
200 µg |
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| AbC109 |
ICAM-2
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CBR-IC2/2 |
Mc |
50 µg |
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| AbC111 |
ICAM-3
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CBR-IC3/1 |
Mc |
50 µg |
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| MIC |
ICAM-3, CD50
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101-1D2 |
Mc |
1 ml |
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| MCD44 |
H-CAM, CD44
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DF1485 |
Mc |
1 ml |
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| MNCA |
N-CAM, RNL-1
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RNL-1 |
Mc |
1 ml |
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| AbC171 |
EpCAM-1
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VU-1D9 |
Mc |
100 µl |
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ELISA detection Kit
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| AbC201 |
sICAM-1 ELISA Kit
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Kit |
1 x 96 wells |
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| AbC236 |
sICAM-2 ELISA Kit
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Kit |
1 x 96 wells |
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| AbC218 |
sICAM-3 ELISA Kit
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Kit |
1 x 96 wells |
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| AbC229 |
sPECAM-1 ELISA Kit
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Kit |
1 x 96 wells |
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| AbC232 |
sVCAM-1 ELISA Kit
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Kit |
1 x 96 wells |
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MMP (Matrix Metalloproteinases)
MMPs are a family of zinc dependant endoproteinases that have well characterized domain structures. They have been implicated in a number of pathologies and normal biological process including : tumor angiogenesis, arthritis, periodontal disease, cardiovascular disease, emphysema, normal development, embryonic development, wound healing, hair follicle cycling, and nerve growth.
extracellular matrix. Picture from Dr Jean Bénard, Institut Gustave Roussy (*1250)
Target species : Human
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| VMA13410 |
MMP 3
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SL-ID3 |
Mc |
100 µg |
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LAMININ
Laminin, a major component of basement membranes, has numerous biological activities including promotion of cell adhesion, migration, growth, and differentiation, including neurite outgrowth. It can be used as a thin coating on tissue-culture surfaces or as a soluble additive to culture medium. Laminin has been shown in culture to stimulate neurite outgrowth, promote cell attachment, chemotaxis, and cell differentation.
Target species : Human
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| VMA1949 |
Laminin-5 [Epiligrin], clone P3E4 (Hu)
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P34 |
Mc |
100 µg |
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| AbC117-1938 |
Laminin
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2D8/33 |
Mc |
50 µl |
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| PLA |
Laminin
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Pc |
250 µl |
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| VMA19562 |
Laminin gamma2 [Laminin 5], clone D4B5 (Hu)
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D4B5 |
Mc |
100 µg |
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Laminin 5 (VMA1949)
Cytoskeleton
Myosins are class of eight molecular motor proteins found in eukaryote tissues. It is one of the key motor systems in cells; it is best known that myosin II plays a major role in both muscle contractions and cytokinesis. Other members of the myosin family have other purposes as well; myosin I and V participate in the transport of membrane vesicles while myosins VI, VII, and XV have functions related to hearing and hair cell stereocilia structure.
Together with actin filaments, myosin provides the mechanism for movement along actin fibers, utilizing energy from ATP. The specific conformational rearrangements throughout the chemo-mechanical transduction process are still not known.
Myosin's structure consists of one or two heavy chains bound to several light chains. Combined, these chains form a protein with a head, neck and tail domain. The size and form of these chains follow the function of the particular myosin.
Target species : Human
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| AbC117-2188 |
cardiac-Myosin
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BGN/04/4482 |
Mc |
200 µg |
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| VMA1549 |
Myosin, skeletal muscle heavy chain
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15F4 |
Mc |
1 mL |
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| MMY |
Myosin
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414 |
Mc |
1 ml |
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ACTIN
Actin is a globular protein that polymerizes helically forming actin filaments (or microfilaments), which like the other two components of the cellular cytoskeleton form a three-dimensional network inside an eukaryotic cell. Actin filaments provide mechanical support for the cell, determine the cell shape, enable cell movements (through lamellipodia, filopodia, or pseudopodia); and participate in certain cell junctions, in cytoplasmic streaming and in contraction of the cell during cytokinesis. In muscle cells they play an essential role, along with myosin, in muscle contraction. In the cytosol, actin is predominantly bound to ATP, but can also bind to ADP. An ATP-actin complex polymerizes faster and dissociates slower than an ADP-actin complex.
Target species : Human
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| Catalog Number |
Description |
Clone |
Type |
Quantity. |
Inf. |
Data |
Price |
Quot. |
| MAC |
Actin
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647 |
Mc |
1 ml |
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| AbC117-5315 |
ACTIN (SARCOMERIC)
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5C5 |
Mc |
5.0ml |
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| VPA3265 |
Actin, gamma
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Pc |
100 µL |
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ARF (ADP Ribosylation factor)
ADP ribosylation factor (ARF) is thought to play a critical role in recruiting coatomer (COPI) to Golgi membranes to drive transport vesicle budding.
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